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ABI3, a component of the WAVE2 complex, is potentially regulated by PI3K/AKT pathway

We previously reported that ABI3 expression is lost in follicular thyroid carcinomas and its restoration significantly inhibited cell growth, invasiveness, migration, and reduced tumor growth in vivo. The mechanistic basis by which ABI3 exerts its tumor suppressive effects is not fully understood. I...

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Detalles Bibliográficos
Autores principales: Moraes, Lais, Zanchin, Nilson I.T., Cerutti, Janete M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620210/
https://www.ncbi.nlm.nih.gov/pubmed/28978070
http://dx.doi.org/10.18632/oncotarget.18840