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Effects of roniciclib in preclinical models of anaplastic thyroid cancer

Many human cancers have altered cyclin-dependent kinase activity. Inhibition of cyclin-dependent kinases may arrest cell cycle progression and represents an important strategy in the treatment of malignancies. We evaluated the therapeutic effects of roniciclib, a cyclin-dependent kinase inhibitor, a...

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Detalles Bibliográficos
Autores principales: Lin, Shu-Fu, Lin, Jen-Der, Hsueh, Chuen, Chou, Ting-Chao, Wong, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620230/
https://www.ncbi.nlm.nih.gov/pubmed/28978090
http://dx.doi.org/10.18632/oncotarget.19092