Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1

Studies suggest that tunicamycin may work as a therapeutic drug to cancer cells by inducing stress in the endoplasmic reticulum (ER) through unfolded protein response (UPR) and thereby promoting apoptosis. However, mechanisms of the prolonged activation of the UPR under sustained ER stress in the re...

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Detalles Bibliográficos
Autores principales: Guha, Prasun, Kaptan, Engin, Gade, Padmaja, Kalvakolanu, Dhananjaya V., Ahmed, Hafiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620248/
https://www.ncbi.nlm.nih.gov/pubmed/28978108
http://dx.doi.org/10.18632/oncotarget.19277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620248/
https://www.ncbi.nlm.nih.gov/pubmed/28978108
http://dx.doi.org/10.18632/oncotarget.19277

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