Acquired tumor cell resistance to sunitinib by increased invasion and epithelial-mesenchymal transition in LL/2 murine lung cancer

OBJECTIVE: This study aims to investigate biological behavior changes in a murine lung cancer cell characterized by acquired resistance to sunitinib, a potent inhibitor of multiple-targeted receptor tyrosine kinase. METHODS: A lung cancer cell line resistant to sunitinib (LL/2-R) was developed from...

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Detalles Bibliográficos
Autores principales: Du, Yang, Liu, Jia-Qi, Tang, Jie, Ge, Jun, Chen, Ye, Cheng, Ke, Ding, Jing, Li, Zhi-Ke, Liu, Ji-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620255/
https://www.ncbi.nlm.nih.gov/pubmed/28978115
http://dx.doi.org/10.18632/oncotarget.19295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620255/
https://www.ncbi.nlm.nih.gov/pubmed/28978115
http://dx.doi.org/10.18632/oncotarget.19295

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