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A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma

BACKGROUND: FKBP51 is a co-chaperone with isomerase activity, abundantly expressed in glioma. We previously identified a spliced isoform (FKBP51s) and highlighted a role for this protein in the upregulation of Programmed Death Ligand 1 (PD-L1) expression in melanoma. Because gliomas can express PD-L...

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Detalles Bibliográficos
Autores principales: D’Arrigo, Paolo, Russo, Michele, Rea, Anna, Tufano, Martina, Guadagno, Elia, Del Basso De Caro, Maria Laura, Pacelli, Roberto, Hausch, Felix, Staibano, Stefania, Ilardi, Gennaro, Parisi, Silvia, Romano, Maria Fiammetta, Romano, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620257/
https://www.ncbi.nlm.nih.gov/pubmed/28978117
http://dx.doi.org/10.18632/oncotarget.19309