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Concurrent somatic mutations in driver genes were significantly correlated with lymph node metastasis and pathological types in solid tumors

To demonstrate the mutational profiles in solid tumors, we profiled 165 solid tumor samples, including 9 cancer types and 4 sample types, by using amplicon-based next-generation sequencing panel covering 48 highly mutated tumorigenesis-related genes that were deep sequenced at an average coverage of...

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Detalles Bibliográficos
Autores principales: Cheng, Yanan, Wang, Shaojing, Han, Lei, Liu, Pengpeng, Li, Hui, Ren, Xiubao, Yu, Jinpu, Hao, Xishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620293/
https://www.ncbi.nlm.nih.gov/pubmed/28978153
http://dx.doi.org/10.18632/oncotarget.19975