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Concurrent somatic mutations in driver genes were significantly correlated with lymph node metastasis and pathological types in solid tumors
To demonstrate the mutational profiles in solid tumors, we profiled 165 solid tumor samples, including 9 cancer types and 4 sample types, by using amplicon-based next-generation sequencing panel covering 48 highly mutated tumorigenesis-related genes that were deep sequenced at an average coverage of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620293/ https://www.ncbi.nlm.nih.gov/pubmed/28978153 http://dx.doi.org/10.18632/oncotarget.19975 |