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Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies

BACKGROUND: Poly-(ADP-Ribose)-Polymerase (PARP) inhibitors are becoming important actors of anti-neoplasic agents landscape, with recent but narrow FDA's approvals for ovarian BRCA mutated cancers and prostatic cancer. Nevertheless, PARP inhibitors are also promising drugs for combined treatmen...

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Detalles Bibliográficos
Autores principales: Lesueur, Paul, Chevalier, François, Austry, Jean-Baptiste, Waissi, Waisse, Burckel, Hélène, Noël, Georges, Habrand, Jean-Louis, Saintigny, Yannick, Joly, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620324/
https://www.ncbi.nlm.nih.gov/pubmed/28978184
http://dx.doi.org/10.18632/oncotarget.19079