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Non-blood circulating tumor DNA detection in cancer

Tumor DNA contains specific somatic alterations that are crucial for the diagnosis and treatment of cancer. Due to the spatial and temporal intra-tumor heterogeneity, multi-sampling is needed to adequately characterize the somatic alterations. Tissue biopsy, however, is limited by the restricted acc...

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Detalles Bibliográficos
Autores principales: Peng, Muyun, Chen, Chen, Hulbert, Alicia, Brock, Malcolm V., Yu, Fenglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620327/
https://www.ncbi.nlm.nih.gov/pubmed/28978187
http://dx.doi.org/10.18632/oncotarget.19942