A Novel Germline Mutation in BRCA1 Causes Exon 20 Skipping in a Korean Family with a History of Breast Cancer

Germline mutations in the BRCA1 and BRCA2 genes are strong genetic factors for predispositions to breast, ovarian, and other related cancers. This report describes a family with a history of breast and ovarian cancers that harbored a novel BRCA1 germline mutation. A single nucleotide deletion in int...

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Detalles Bibliográficos
Autores principales: Yoon, Kyong-Ah, Kong, Sun-Young, Lee, Eun Ji, Cho, Jeong Nam, Chang, Suhwan, Lee, Eun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620447/
https://www.ncbi.nlm.nih.gov/pubmed/28970858
http://dx.doi.org/10.4048/jbc.2017.20.3.310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620447/
https://www.ncbi.nlm.nih.gov/pubmed/28970858
http://dx.doi.org/10.4048/jbc.2017.20.3.310

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