Development and Characterization of an Amorphous Solid Dispersion of Furosemide in the Form of a Sublingual Bioadhesive Film to Enhance Bioavailability

Administered by an oral route, Furosemide (FUR), a diuretic used in several edematous states and hypertension, presents bioavailability problems, reported as a consequence of an erratic gastrointestinal absorption due to various existing polymorphic forms and low and pH-dependent solubility. A mucoa...

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Detalles Bibliográficos
Autores principales: De Caro, Viviana, Ajovalasit, Alessia, Sutera, Flavia Maria, Murgia, Denise, Sabatino, Maria Antonietta, Dispenza, Clelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620563/
https://www.ncbi.nlm.nih.gov/pubmed/28672810
http://dx.doi.org/10.3390/pharmaceutics9030022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620563/
https://www.ncbi.nlm.nih.gov/pubmed/28672810
http://dx.doi.org/10.3390/pharmaceutics9030022

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