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Multiple Functions of D-α-Tocopherol Polyethylene Glycol 1000 Succinate (TPGS) as Curcumin Nanoparticle Stabilizer: In Vivo Kinetic Profile and Anti-Ulcerative Colitis Analysis in Animal Model

This study was conducted to evaluate the potential benefit of particle reduction down to nanoscale on curcumin, a unique natural active compound facing therapeutic problems due to low solubility and permeability. In addition, the presence of TPGS as a surfactant for multiple functions on curcumin na...

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Detalles Bibliográficos
Autores principales: Rachmawati, Heni, Pradana, Aditya Trias, Safitri, Dewi, Adnyana, I Ketut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620565/
https://www.ncbi.nlm.nih.gov/pubmed/28754010
http://dx.doi.org/10.3390/pharmaceutics9030024