Pharmacokinetic and Toxicodynamic Characterization of a Novel Doxorubicin Derivative

Doxorubicin (Dox) is an effective anti-cancer medication with poor oral bioavailability and systemic toxicities. DoxQ was developed by conjugating Dox to the lymphatically absorbed antioxidant quercetin to improve Dox’s bioavailability and tolerability. The purpose of this study was to characterize...

Descripción completa

Detalles Bibliográficos
Autores principales: Alrushaid, Samaa, Sayre, Casey L., Yáñez, Jaime A., Forrest, M. Laird, Senadheera, Sanjeewa N., Burczynski, Frank J., Löbenberg, Raimar, Davies, Neal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620576/
https://www.ncbi.nlm.nih.gov/pubmed/28902176
http://dx.doi.org/10.3390/pharmaceutics9030035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620576/
https://www.ncbi.nlm.nih.gov/pubmed/28902176
http://dx.doi.org/10.3390/pharmaceutics9030035

Ejemplares similares