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Synthesis and Antiproliferative Activity of Novel Heterocyclic Indole-Trimethoxyphenyl Conjugates

The synthesis and biological evaluation of a series of novel heterocyclic indole derivatives is described. The consolidation of the combretastatin and bisindolylmaleimide templates towards the inclusion of a novel heterocyclic ring proffered a versatile pharmacophore with which to pursue chemical di...

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Detalles Bibliográficos
Autores principales: Cahill, Michael M., O’Shea, Kevin D., Pierce, Larry T., Winfield, Hannah J., Eccles, Kevin S., Lawrence, Simon E., McCarthy, Florence O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620606/
https://www.ncbi.nlm.nih.gov/pubmed/28678205
http://dx.doi.org/10.3390/ph10030062