Comparison of In Vitro Assays in Selecting Radiotracers for In Vivo P-Glycoprotein PET Imaging

Positron emission tomography (PET) imaging of P-glycoprotein (P-gp) in the blood-brain barrier can be important in neurological diseases where P-gp is affected, such as Alzheimer´s disease. Radiotracers used in the imaging studies are present at very small, nanomolar, concentration, whereas in vitro...

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Detalles Bibliográficos
Autores principales: Raaphorst, Renske M., Savolainen, Heli, Cantore, Mariangela, van de Steeg, Evita, van Waarde, Aren, Colabufo, Nicola A., Elsinga, Philip H., Lammertsma, Adriaan A., Windhorst, Albert D., Luurtsema, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620620/
https://www.ncbi.nlm.nih.gov/pubmed/29036881
http://dx.doi.org/10.3390/ph10030076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620620/
https://www.ncbi.nlm.nih.gov/pubmed/29036881
http://dx.doi.org/10.3390/ph10030076

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