HDAC6 Brain Mapping with [(18)F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

[Image: see text] Histone deacetylase 6 (HDAC6) function and dysregulation have been implicated in the etiology of certain cancers and more recently in central nervous system (CNS) disorders including Rett syndrome, Alzheimer’s and Parkinson’s diseases, and major depressive disorder. HDAC6-selective...

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Detalles Bibliográficos
Autores principales: Strebl, Martin G., Campbell, Arthur J., Zhao, Wen-Ning, Schroeder, Frederick A., Riley, Misha M., Chindavong, Peter S., Morin, Thomas M., Haggarty, Stephen J., Wagner, Florence F., Ritter, Tobias, Hooker, Jacob M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620987/
https://www.ncbi.nlm.nih.gov/pubmed/28979942
http://dx.doi.org/10.1021/acscentsci.7b00274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620987/
https://www.ncbi.nlm.nih.gov/pubmed/28979942
http://dx.doi.org/10.1021/acscentsci.7b00274

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