Multi-target-directed phenol–triazole ligands as therapeutic agents for Alzheimer's disease

Alzheimer's disease (AD) is a multifactorial disease that is characterized by the formation of intracellular neurofibrillary tangles and extracellular amyloid-β (Aβ) plaque deposits. Increased oxidative stress, metal ion dysregulation, and the formation of toxic Aβ peptide oligomers are all con...

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Detalles Bibliográficos
Autores principales: Jones, Michael R., Mathieu, Emilie, Dyrager, Christine, Faissner, Simon, Vaillancourt, Zavier, Korshavn, Kyle J., Lim, Mi Hee, Ramamoorthy, Ayyalusamy, Wee Yong, V., Tsutsui, Shigeki, Stys, Peter K., Storr, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621006/
https://www.ncbi.nlm.nih.gov/pubmed/28989601
http://dx.doi.org/10.1039/c7sc01269a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621006/
https://www.ncbi.nlm.nih.gov/pubmed/28989601
http://dx.doi.org/10.1039/c7sc01269a

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