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Stimuli-responsive nucleic acid-functionalized metal–organic framework nanoparticles using pH- and metal-ion-dependent DNAzymes as locks

A versatile approach to modify metal–organic framework nanoparticles (NMOFs) with nucleic acid tethers, using the “click chemistry” method is introduced. The nucleic acid-functionalized NMOFs are used to prepare stimuli-responsive carriers of loads (fluorescence probes or anti-cancer drugs). Two dif...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Hai, Yu, Xu, Cecconello, Alessandro, Sohn, Yang Sung, Nechushtai, Rachel, Willner, Itamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621505/
https://www.ncbi.nlm.nih.gov/pubmed/28989617
http://dx.doi.org/10.1039/c7sc01765k