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HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication

Hepatitis C virus (HCV) induces autophagy to promote its replication, including its RNA replication, which can take place on double-membrane vesicles known as autophagosomes. However, how HCV induces the biogenesis of autophagosomes and how HCV RNA replication complex may be assembled on autophagoso...

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Detalles Bibliográficos
Autores principales: Wang, Linya, Kim, Ja Yeon, Liu, Helene Minyi, Lai, Michael M. C., Ou, Jing-hsiung James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621699/
https://www.ncbi.nlm.nih.gov/pubmed/28931085
http://dx.doi.org/10.1371/journal.ppat.1006609