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NLRC4 regulates caspase-1 and IL-1beta production in a CD11b(low)Ly6G(low) population of cells required for resistance to Pseudomonas aeruginosa keratitis

Psbetaeudomonas (P.) aeruginosa infection of the cornea in BALB/c mice does not result in perforation and the mice have been classified as resistant. However, regulation of this response via inflammasome activation remained untested. Therefore, BALB/c mice were infected with P. aeruginosa ATCC strai...

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Detalles Bibliográficos
Autores principales: McClellan, Sharon A., Jerome, Andrew, Suvas, Susmit, Hazlett, Linda D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621704/
https://www.ncbi.nlm.nih.gov/pubmed/28961278
http://dx.doi.org/10.1371/journal.pone.0185718