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Hepatitis C Virus Infection Increases c-Jun N-Terminal Kinase (JNK) Phosphorylation and Accentuates Hepatocyte Lipoapoptosis

BACKGROUND: Hepatitis C virus (HCV) infection and metabolic diseases including nonalcoholic steatohepatitis (NASH) exhibit a complex interplay. Although free fatty acid-mediated apoptosis is a prominent feature of NASH, the impact of HCV infection on hepatocyte lipotoxicity has remained largely unex...

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Detalles Bibliográficos
Autores principales: Takaki, Hiroko, Akazawa, Yuko, Kido, Youko, Morishita, Mami, Honda, Takuya, Shibata, Hidetaka, Miuma, Satoshi, Miyaaki, Hisamitsu, Taura, Naota, Kondo, Hisayoshi, Nakao, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621789/
https://www.ncbi.nlm.nih.gov/pubmed/28931802
http://dx.doi.org/10.12659/MSM.903210