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Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction

Transcriptionally activated monocytes are recruited to the heart after acute myocardial infarction (AMI). After AMI in mice and humans, the number of extracellular vesicles (EVs) increased acutely. In humans, EV number correlated closely with the extent of myocardial injury. We hypothesized that EVs...

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Detalles Bibliográficos
Autores principales: Akbar, Naveed, Digby, Janet E., Cahill, Thomas J., Tavare, Abhijeet N., Corbin, Alastair L., Saluja, Sushant, Dawkins, Sam, Edgar, Laurienne, Rawlings, Nadiia, Ziberna, Klemen, McNeill, Eileen, Johnson, Errin, Aljabali, Alaa A., Dragovic, Rebecca A., Rohling, Mala, Belgard, T. Grant, Udalova, Irina A., Greaves, David R., Channon, Keith M., Riley, Paul R., Anthony, Daniel C., Choudhury, Robin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621885/
https://www.ncbi.nlm.nih.gov/pubmed/28878126
http://dx.doi.org/10.1172/jci.insight.93344