A general method to fine-tune fluorophores for live-cell and in vivo imaging

Pushing the frontier of fluorescence microscopy requires the design of enhanced fluorophores with finely tuned properties. We recently discovered that incorporation of four-membered azetidine rings into classic fluorophore structures elicits substantial increases in brightness and photostability, re...

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Detalles Bibliográficos
Autores principales: Grimm, Jonathan B., Muthusamy, Anand K., Liang, Yajie, Brown, Timothy A., Lemon, William C., Patel, Ronak, Lu, Rongwen, Macklin, John J., Keller, Phillip J., Ji, Na, Lavis, Luke D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621985/
https://www.ncbi.nlm.nih.gov/pubmed/28869757
http://dx.doi.org/10.1038/nmeth.4403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621985/
https://www.ncbi.nlm.nih.gov/pubmed/28869757
http://dx.doi.org/10.1038/nmeth.4403

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