Synthesis and biological evaluation of tricyclic matrinic derivatives as a class of novel anti-HCV agents

BACKGROUND: 12N-benzyl matrinic acid analogues had been identified to be a novel scaffold of anti-HCV agents with a specific mechanism, and the representative compound 1 demonstrated a moderate anti-HCV activity. The intensive structure–activity relationship of this kind of compounds is explored so...

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Detalles Bibliográficos
Autores principales: Tang, Sheng, Peng, Zong-Gen, Li, Ying-Hong, Zhang, Xin, Fan, Tian-Yun, Jiang, Jian-Dong, Wang, Yan-Xiang, Song, Dan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622025/
https://www.ncbi.nlm.nih.gov/pubmed/29086870
http://dx.doi.org/10.1186/s13065-017-0327-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622025/
https://www.ncbi.nlm.nih.gov/pubmed/29086870
http://dx.doi.org/10.1186/s13065-017-0327-8

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