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Synthesis and biological evaluation of tricyclic matrinic derivatives as a class of novel anti-HCV agents
BACKGROUND: 12N-benzyl matrinic acid analogues had been identified to be a novel scaffold of anti-HCV agents with a specific mechanism, and the representative compound 1 demonstrated a moderate anti-HCV activity. The intensive structure–activity relationship of this kind of compounds is explored so...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622025/ https://www.ncbi.nlm.nih.gov/pubmed/29086870 http://dx.doi.org/10.1186/s13065-017-0327-8 |