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Synthetic microparticles conjugated with VEGF(165) improve the survival of endothelial progenitor cells via microRNA-17 inhibition

Several cell-based therapies are under pre-clinical and clinical evaluation for the treatment of ischemic diseases. Poor survival and vascular engraftment rates of transplanted cells force them to work mainly via time-limited paracrine actions. Although several approaches, including the use of solub...

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Detalles Bibliográficos
Autores principales: Aday, Sezin, Zoldan, Janet, Besnier, Marie, Carreto, Laura, Saif, Jaimy, Fernandes, Rui, Santos, Tiago, Bernardino, Liliana, Langer, Robert, Emanueli, Costanza, Ferreira, Lino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622042/
https://www.ncbi.nlm.nih.gov/pubmed/28963481
http://dx.doi.org/10.1038/s41467-017-00746-7