Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling

Inflammation influences cancer development, progression, and the efficacy of cancer treatments, yet the mechanisms by which immune signaling drives alterations in the cancer cell transcriptome remain unclear. Using ChIP-seq, RNA-seq, and GRO-seq, here we demonstrate a global overlap in the binding o...

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Detalles Bibliográficos
Autores principales: Rahnamoun, Homa, Lu, Hanbin, Duttke, Sascha H., Benner, Christopher, Glass, Christopher K., Lauberth, Shannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622043/
https://www.ncbi.nlm.nih.gov/pubmed/28963538
http://dx.doi.org/10.1038/s41467-017-01117-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622043/
https://www.ncbi.nlm.nih.gov/pubmed/28963538
http://dx.doi.org/10.1038/s41467-017-01117-y

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