Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin

The Cys2/His2-type zinc finger protein Zfp296 has been implicated in stem cell pluripotency and tumor pathogenesis. However, its mechanisms remain elusive. Here, we demonstrated that a Zfp296 deficiency in mice impairs germ-cell development and embryonic growth. Zfp296 was intracellularly localized...

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Detalles Bibliográficos
Autores principales: Matsuura, Takumi, Miyazaki, Satsuki, Miyazaki, Tatsushi, Tashiro, Fumi, Miyazaki, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622089/
https://www.ncbi.nlm.nih.gov/pubmed/28963472
http://dx.doi.org/10.1038/s41598-017-12772-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622089/
https://www.ncbi.nlm.nih.gov/pubmed/28963472
http://dx.doi.org/10.1038/s41598-017-12772-y

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