Epithelial Chloride Transport by CFTR Requires TMEM16A

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is the secretory chloride/bicarbonate channel in airways and intestine that is activated through ATP binding and phosphorylation by protein kinase A, but fails to operate in cystic fibrosis (CF). TMEM16A (also known as anoctamin 1, ANO1) is...

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Detalles Bibliográficos
Autores principales: Benedetto, Roberta, Ousingsawat, Jiraporn, Wanitchakool, Podchanart, Zhang, Yong, Holtzman, Michael J., Amaral, Margarida, Rock, Jason R., Schreiber, Rainer, Kunzelmann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622110/
https://www.ncbi.nlm.nih.gov/pubmed/28963502
http://dx.doi.org/10.1038/s41598-017-10910-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622110/
https://www.ncbi.nlm.nih.gov/pubmed/28963502
http://dx.doi.org/10.1038/s41598-017-10910-0

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