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Regioselectivity and diastereoselectivity of three-component reaction of α-amino acid, dialkyl acetylenedicarboxylates and 2-arylidene-1,3-indanediones

The 1,3-dipolar cycloaddition of active azomethine ylide, which were generated in situ from addition reaction of α-amino acids with dialkyl acetylenedicarboxylates, with 2-arylidene-1,3-indanediones showed versatile regioselectivity and diastereoselectivity. The reaction of sarcosine and glycine aff...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Sun, Jing, Huang, Ying, Zhang, Yu, Yan, Chao-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622111/
https://www.ncbi.nlm.nih.gov/pubmed/28963495
http://dx.doi.org/10.1038/s41598-017-12361-z