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Selection on start codons in prokaryotes and potential compensatory nucleotide substitutions

Reconstruction of the evolution of start codons in 36 groups of closely related bacterial and archaeal genomes reveals purifying selection affecting AUG codons. The AUG starts are replaced by GUG and especially UUG significantly less frequently than expected under the neutral expectation derived fro...

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Detalles Bibliográficos
Autores principales: Belinky, Frida, Rogozin, Igor B., Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622118/
https://www.ncbi.nlm.nih.gov/pubmed/28963504
http://dx.doi.org/10.1038/s41598-017-12619-6