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Interplay between 3′-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke

Stroke incidence is a multifactorial disease and especially hyperhomocysteinemia is associated with a higher risk of stroke. Previous studies have reported a folate metabolism disorder associated with the MTHFR gene. We investigated four single nucleotide polymorphisms in the MTHFR 3′-UTR [2572 C &g...

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Detalles Bibliográficos
Autores principales: Kim, Jung Oh, Park, Han Sung, Ryu, Chang Soo, Shin, Jung-Won, Kim, Jinkwon, Oh, Seung Hun, Kim, Ok Joon, Kim, Nam Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622127/
https://www.ncbi.nlm.nih.gov/pubmed/28963520
http://dx.doi.org/10.1038/s41598-017-12668-x