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Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains

Dopamine regulates reward, cognition, and locomotor functions. By mediating rapid reuptake of extracellular dopamine, the dopamine transporter is critical for spatiotemporal control of dopaminergic neurotransmission. Here, we use super-resolution imaging to show that the dopamine transporter is dyna...

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Detalles Bibliográficos
Autores principales: Rahbek-Clemmensen, Troels, Lycas, Matthew D., Erlendsson, Simon, Eriksen, Jacob, Apuschkin, Mia, Vilhardt, Frederik, Jørgensen, Trine N., Hansen, Freja H., Gether, Ulrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622129/
https://www.ncbi.nlm.nih.gov/pubmed/28963530
http://dx.doi.org/10.1038/s41467-017-00790-3