Altered brain and gut responses to corticotropin-releasing hormone (CRH) in patients with irritable bowel syndrome

Stress is a known trigger of irritable bowel syndrome (IBS) and exacerbates its gastrointestinal symptoms. However, underlying the physiological mechanism remains unknown. Here, we investigated hypothalamic–pituitary–adrenal (HPA) axis, colonic motility, and autonomic responses to corticotropin-rele...

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Detalles Bibliográficos
Autores principales: Kano, Michiko, Muratsubaki, Tomohiko, Van Oudenhove, Lukas, Morishita, Joe, Yoshizawa, Makoto, Kohno, Keiji, Yagihashi, Mao, Tanaka, Yukari, Mugikura, Shunji, Dupont, Patrick, Ly, Huynh Giao, Takase, Kei, Kanazawa, Motoyori, Fukudo, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622133/
https://www.ncbi.nlm.nih.gov/pubmed/28963545
http://dx.doi.org/10.1038/s41598-017-09635-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622133/
https://www.ncbi.nlm.nih.gov/pubmed/28963545
http://dx.doi.org/10.1038/s41598-017-09635-x

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