Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells

Regulatory T cells (Tregs) control key events of immune tolerance, primarily by suppression of effector T cells. We previously revealed that Tregs rapidly suppress T cell receptor (TCR)-induced calcium store depletion in conventional CD4(+)CD25(−) T cells (Tcons) independently of IP(3) levels, conse...

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Detalles Bibliográficos
Autores principales: Joshi, Rubin N., Binai, Nadine A., Marabita, Francesco, Sui, Zhenhua, Altman, Amnon, Heck, Albert J. R., Tegnér, Jesper, Schmidt, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622166/
https://www.ncbi.nlm.nih.gov/pubmed/28993769
http://dx.doi.org/10.3389/fimmu.2017.01163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622166/
https://www.ncbi.nlm.nih.gov/pubmed/28993769
http://dx.doi.org/10.3389/fimmu.2017.01163

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