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Continuous Release of Tumor-Derived Factors Improves the Modeling of Cachexia in Muscle Cell Culture

Cachexia is strongly associated with a poor prognosis in cancer patients but the biological trigger is unknown and therefore no therapeutics exist. The loss of skeletal muscle is the most deleterious aspect of cachexia and it appears to depend on secretions from tumor cells. Models for studying wast...

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Detalles Bibliográficos
Autores principales: Jackman, Robert W., Floro, Jess, Yoshimine, Rei, Zitin, Brian, Eiampikul, Maythita, El-Jack, Khalid, Seto, Danielle N., Kandarian, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622188/
https://www.ncbi.nlm.nih.gov/pubmed/28993738
http://dx.doi.org/10.3389/fphys.2017.00738