TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells

The plasticity of myeloid cells is illustrated by a diversity of functions including their role as effectors of innate immunity as macrophages (MACs) and bone remodelling as osteoclasts (OCs). TET2, a methylcytosine dioxygenase highly expressed in these cells and frequently mutated in myeloid leukem...

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Detalles Bibliográficos
Autores principales: Garcia-Gomez, Antonio, Li, Tianlu, Kerick, Martin, Català-Moll, Francesc, Comet, Natalia R., Rodríguez-Ubreva, Javier, de la Rica, Lorenzo, Branco, Miguel R., Martín, Javier, Ballestar, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622316/
https://www.ncbi.nlm.nih.gov/pubmed/28973458
http://dx.doi.org/10.1093/nar/gkx666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622316/
https://www.ncbi.nlm.nih.gov/pubmed/28973458
http://dx.doi.org/10.1093/nar/gkx666

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