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The abundance of Fob1 modulates the efficiency of rRFBs to stall replication forks

In eukaryotes, ribosomal genes (rDNA) are organized in tandem repeats localized in one or a few clusters. Each repeat encompasses a transcription unit and a non-transcribed spacer. Replication forks moving in the direction opposite to transcription are blocked at specific sites called replication fo...

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Detalles Bibliográficos
Autores principales: Castán, Alicia, Hernández, Pablo, Krimer, Dora B., Schvartzman, Jorge B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622318/
https://www.ncbi.nlm.nih.gov/pubmed/28973451
http://dx.doi.org/10.1093/nar/gkx655