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p53 regulates enhancer accessibility and activity in response to DNA damage
The tumor suppressor p53 is a well-characterized transcription factor that can bind gene promoters and regulate target gene transcription in response to DNA damage. Recent studies, however, have revealed that p53 binding events occur predominantly within regulatory enhancer elements. The effect of p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622327/ https://www.ncbi.nlm.nih.gov/pubmed/28973438 http://dx.doi.org/10.1093/nar/gkx577 |