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p53 regulates enhancer accessibility and activity in response to DNA damage

The tumor suppressor p53 is a well-characterized transcription factor that can bind gene promoters and regulate target gene transcription in response to DNA damage. Recent studies, however, have revealed that p53 binding events occur predominantly within regulatory enhancer elements. The effect of p...

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Detalles Bibliográficos
Autores principales:	Younger, Scott T., Rinn, John L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622327/ https://www.ncbi.nlm.nih.gov/pubmed/28973438 http://dx.doi.org/10.1093/nar/gkx577

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