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Decomposing protein–DNA binding and recognition using simplified protein models

We analyze the role of different physicochemical factors in protein/DNA binding and recognition by comparing the results from all-atom molecular dynamics simulations with simulations using simplified protein models. These models enable us to separate the role of specific amino acid side chains, form...

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Detalles Bibliográficos
Autores principales: Etheve, Loïc, Martin, Juliette, Lavery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622342/
https://www.ncbi.nlm.nih.gov/pubmed/28973439
http://dx.doi.org/10.1093/nar/gkx627