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Targeted chromatin ligation, a robust epigenetic profiling technique for small cell numbers
The complexity and inefficiency of chromatin immunoprecipitation strategies restrict their sensitivity and application when examining rare cell populations. We developed a new technique that replaces immunoprecipitation with a simplified chromatin fragmentation and proximity ligation step that elimi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622369/ https://www.ncbi.nlm.nih.gov/pubmed/28973448 http://dx.doi.org/10.1093/nar/gkx648 |