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Dual function of Swc5 in SWR remodeling ATPase activation and histone H2A eviction

The chromatin remodeler SWR deposits histone H2A.Z at promoters and other regulatory sites via an ATP-driven histone exchange reaction that replaces nucleosomal H2A with H2A.Z. Simultaneous binding of SWR to both H2A nucleosome and free H2A.Z induces SWR ATPase activity and engages the histone excha...

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Detalles Bibliográficos
Autores principales: Sun, Lu, Luk, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622370/
https://www.ncbi.nlm.nih.gov/pubmed/28973436
http://dx.doi.org/10.1093/nar/gkx589