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β-catenin-mediated YAP signaling promotes human glioma growth

BACKGROUND: Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression.We and others find that YAP is up-regulated in human gliomas and associated with worse prognosis of patients. However, the role and mechanism...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Pan, Peng, Wang, Zhaohao, Zhang, Yu, Xie, Peng, Geng, Decheng, Jiang, Yang, Yu, Rutong, Zhou, Xiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622484/
https://www.ncbi.nlm.nih.gov/pubmed/28962630
http://dx.doi.org/10.1186/s13046-017-0606-1