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Statistical prediction of immunity to placental malaria based on multi-assay antibody data for malarial antigens

BACKGROUND: Plasmodium falciparum infections are especially severe in pregnant women because infected erythrocytes (IE) express VAR2CSA, a ligand that binds to placental trophoblasts, causing IE to accumulate in the placenta. Resulting inflammation and pathology increases a woman’s risk of anemia, m...

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Detalles Bibliográficos
Autores principales: Siriwardhana, Chathura, Fang, Rui, Salanti, Ali, Leke, Rose G. F., Bobbili, Naveen, Taylor, Diane Wallace, Chen, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622501/
https://www.ncbi.nlm.nih.gov/pubmed/28962616
http://dx.doi.org/10.1186/s12936-017-2041-3