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Statistical prediction of immunity to placental malaria based on multi-assay antibody data for malarial antigens
BACKGROUND: Plasmodium falciparum infections are especially severe in pregnant women because infected erythrocytes (IE) express VAR2CSA, a ligand that binds to placental trophoblasts, causing IE to accumulate in the placenta. Resulting inflammation and pathology increases a woman’s risk of anemia, m...
Autores principales: | Siriwardhana, Chathura, Fang, Rui, Salanti, Ali, Leke, Rose G. F., Bobbili, Naveen, Taylor, Diane Wallace, Chen, John J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622501/ https://www.ncbi.nlm.nih.gov/pubmed/28962616 http://dx.doi.org/10.1186/s12936-017-2041-3 |
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