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Identification of a novel linear B-cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates
BACKGROUND: The Nucleoprotein (NP) is the most abundant and highly immunogenic protein in canine distemper virus (CDV), playing an important role in CDV viral replication and assembly. RESULTS: In this study, a specific monoclonal antibody, named C8, was produced against the NP protein C terminal (a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622507/ https://www.ncbi.nlm.nih.gov/pubmed/28962633 http://dx.doi.org/10.1186/s12985-017-0858-6 |