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Novel technologies combined with traditional metabolic engineering strategies facilitate the construction of shikimate-producing Escherichia coli
Shikimate is an important intermediate in the aromatic amino acid pathway, which can be used as a promising building block for the synthesis of biological compounds, such as neuraminidase inhibitor Oseltamivir (Tamiflu(®)). Compared with traditional methods, microbial production of shikimate has the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622527/ https://www.ncbi.nlm.nih.gov/pubmed/28962609 http://dx.doi.org/10.1186/s12934-017-0773-y |