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Cellular fatty acid synthase is required for late stages of HIV-1 replication

BACKGROUND: Like all viruses, HIV-1 relies on host systems to replicate. The human purinome consists of approximately two thousand proteins that bind and use purines such as ATP, NADH, and NADPH. By virtue of their purine binding pockets, purinome proteins are highly druggable, and many existing dru...

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Detalles Bibliográficos
Autores principales: Kulkarni, Manjusha M., Ratcliff, Annette N., Bhat, Menakshi, Alwarawrah, Yazan, Hughes, Philip, Arcos, Jesus, Loiselle, David, Torrelles, Jordi B., Funderburg, Nicholas T., Haystead, Timothy A., Kwiek, Jesse J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622536/
https://www.ncbi.nlm.nih.gov/pubmed/28962653
http://dx.doi.org/10.1186/s12977-017-0368-z