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Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer’s disease, and neuronal injury in humans: a cohort study

BACKGROUND: Surgery and anesthesia have been linked to postoperative cognitive disturbance and increased risk of Alzheimer’s disease. It is not clear by which mechanisms this increased risk for cognitive disease is mediated. Further, amyloid β production has been suggested to depend on the sleep-wak...

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Detalles Bibliográficos
Autores principales: Pikwer, Andreas, Castegren, Markus, Namdar, Sijal, Blennow, Kaj, Zetterberg, Henrik, Mattsson, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622541/
https://www.ncbi.nlm.nih.gov/pubmed/28962579
http://dx.doi.org/10.1186/s12974-017-0950-2