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Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer’s disease, and neuronal injury in humans: a cohort study
BACKGROUND: Surgery and anesthesia have been linked to postoperative cognitive disturbance and increased risk of Alzheimer’s disease. It is not clear by which mechanisms this increased risk for cognitive disease is mediated. Further, amyloid β production has been suggested to depend on the sleep-wak...
Autores principales: | Pikwer, Andreas, Castegren, Markus, Namdar, Sijal, Blennow, Kaj, Zetterberg, Henrik, Mattsson, Niklas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622541/ https://www.ncbi.nlm.nih.gov/pubmed/28962579 http://dx.doi.org/10.1186/s12974-017-0950-2 |
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